The present work is part of a research effort aimed at integrating a detailed model of airflow in large spaces with an algebraic multizone infiltration model to describe pollutant transport and coupled air flows within and between complex buildings and large spaces. In the past 15 years, zonal models were developed with the goal to obtain an approximate prediction of airflow characteristics in large indoor spaces. Also, reducing the number of grids in CFD models is a natural way of decreasing their demand of computational resources to solve air flows in room.