Source/sink models of volatile organic compound (VOC) emissions from building materials are reviewed and a multi-zone ventilation model is developed to predict concentrations of contaminants in rooms. The source model based on the principles of mass transfer and fluid flow presented by Zhang et al. (1995, 1996) is integrated into the multi-zone ventilation model. The characteristics of the parameters related to voc concentration, i.e. Schmidt number, ventilation rate and air velocity at the free stream are investigated by the sensitivity analysis.