The focus of this paper is on controlling ventilation rate to provide acceptable temperature and relative humidity in the space being ventilated. To this end, a system of heat and moisture balance equations for building indoor and components is described. The system is solved numerically. Based on a series of indoor temperature and moisture measurements for our experimental house and well-mixed air distribution in room, moisture generation rate is estimated. The model is validated by simulating the experimental house. Good agreement between the simulated and measured results is obtained.