A cross-sectional study was carried out to investigate the occurrence of the sick building syndrome (SBS) among office workers in Mauritius. A walk-through inspection and a questionnaire survey were carried out in 21 office building complexes to evaluate the prevalence of risk indicators for SBS symptoms among 302 office workers. Indoor climatic variables monitored were: carbon dioxide, carbon monoxide, nitrogen dioxide, air temperature, relative humidity, air movement, noise and light. All data collected were analysed using the EPl-info software.