It is well known that the introduction of tracer gas techniques to ventilation studies has provided much useful information that used to be unattainable from conventional measuring techniques. Data acquisition systems (DASs) containing analog-to-digital (ND) converters are usually used to perform the key role which is reading and saving signals to storage in digital format. In the measuring process, there are a number of components in the measuring equipment which may produce system-based noise fluctuations to the final result.