Nosocomial infectior1s are a major problem in many hospital buildings, with ,approximately 10% of patients acquiring such an infection during a hospital stay. Airborne transmission is one of the important routes for a number of nosocomial pathogens. To combat this proq,lem there are a number of engineering control strategies, such as the use of ultraviolet germicidal irradiation and advanced ventilation techniques, which can be used. This paper outlines the 'state of the art' in air disinfection, and reviews recent research work in this field.