Measurements of air flow and microorganism concentration have been made in the stair shafts of a hospital, using a diving bell-type of pressure-recording instrument, and a sampler for the microorganisms, respectively. Results of experiments were used to calculate the flow rate of microorganisms between the floors of the hospital. A mathematical model based on simplified transport equations is proposed, which would allow the prediction of the flow field and the distribution of microorganisms in the stair shaft.