CFD dynamic simulation on air movement in negative pressure isolation room using dynamic mesh model

The aim of negative pressure control in an isolation room is to control the airflow so as to control the movement of airborne infectious particles. The differential pressure between isolation room and adjacent ambient areas should control the direction of airflow from clean to less clean areas. But operations such as the opening or closing of the door between the two areas would destroy the differential pressure.
In this paper , CFD analysis was performed to examine the characteristics of airflow between isolation room and adjacent ambient areas in the process of door opening, door closing and people walking through the door. The dynamic mesh model was used. Results and are presented.